Fatigue is a state of awareness describing a range of afflictions, usually associated with physical and/or mental weakness, though varying from a general state of lethargy to a specific work-induced burning sensation within one's muscles. Fatigue is a non-specific symptom, which means that it has many possible causes. Fatigue is considered a symptom, as opposed to a medical sign, because it is reported by the patient instead of being observed by others. 
  • ginseng
    High doses of the herb American ginseng helped patients fight cancer-related fatigue, according to Mayo Clinic researchers.
  • Sleep actually may improve with age, opposite of what was previously thought
    It is generally thought that older people tend to suffer poorer sleep than their younger counterparts, but researchers in a recent study reveal the opposite, that sleep quality appears to improve over a lifetime.
  • Citing poor quality control in a number of specific experiments, the journal Science has retracted an October 2009 study investigating chronic fatigue syndrome (CFS) identifying an infectious retrovirus called xenotropic murine leukemia (XMRV) in a majority of the patients affected by CFS.
  • UPS employees load containers onto an aircraft at the World Port air hub during a visit by U.S. Treasury Secretary Timothy Geithner in Louisville, Kentucky September 26, 2011.
    The Independent Pilots Association (IPA) filed a Petition for Review in the U.S. Court of Appeals for the D.C. Circuit on Thursday in order to challenge FAA's exclusion of cargo operations from the final flight and duty time rule.
  • Living with breast cancer
    Women treating breast cancer with chemotherapy may experience exhaustion for a years following treatment, a new study confirms.
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    Researchers have rejected the link between chronic fatigue syndrome and the XMRV virus as the disease's cause.
  • A group of 26 of the nation's leaders in medicine, health care, patient safety, and research today called for sweeping changes in the design, supervision and financing of U.S. hospital residency care programs to protect patients from serious, preventable medical errors, and end dangerously long work hours for physicians in training.
  • Chronic fatigue syndrome (CFS) is characterized by unexplained and debilitating tiredness and is associated with headaches, disrupted sleep, muscle pain and difficulty in concentrating. New research published by BioMed Central's open access journal BMC Medicine shows that ethnicity, depression, lack of exercise or social support, and social difficulties are major risk factors for CFS.
  • Poor sleep quality is associated with greater disability in rheumatoid arthritis patients
    A study in the Feb. 15 issue of the Journal of Clinical Sleep Medicine found that poor sleep quality correlated with higher levels of depressive symptoms, greater pain severity, increased fatigue, and greater functional disability in patients with Rheumatoid Arthritis (RA). The study suggests that addressing sleep problems via pharmacological or behavioral interventions may have a critical impact on the health and lives of patients with RA.
  • What can scientists learn from watching a group of people sitting around, chatting, playing movies, reading, and happily making new friends? Quite a lot, says University of Melbourne, Australia acoustician Adam Vogel, who carefully observed this sort of group in a fatigue management study he and his colleagues describe this month in The Journal of the Acoustical Society of America.
  • Researchers at Vanderbilt University have "engineered" a mouse that can run on a treadmill twice as long as a normal mouse by increasing its supply of acetylcholine, the neurotransmitter essential for muscle contraction.
  • Nearly three-quarters of patients with Parkinson's disease experience fatigue or excessive daytime sleepiness (EDS), but clinicians should assess both problems separately in order to improve the profession's understanding of their distinct, but overlapping, physiology.