Liver Disease

  • Treatment of inoperable advanced liver cancer with the agent doxorubicin (routinely used to treat this condition) in addition to the agent sorafenib resulted in greater overall survival and progression-free survival, compared to patients who received treatment with doxorubicin alone, according to a study in the November 17 issue of JAMA.
  • Specific, relatively uncommon variations at a region of human chromosome 8 have recently been linked to fat (lipid) levels in the blood that decrease an individual's risk of atherosclerosis (a disease of the major arterial blood vessels that is a main cause of heart attack and stroke).
  • Scientists from Weill Cornell Medical College have found that endothelial cells play a key role in regeneration of liver, giving hope to new treatments for restoring liver and bone marrow.
  • Alcohol does much more harm to the body than just damaging the liver. Drinking also can weaken the immune system, slow healing, impair bone formation, increase the risk of HIV transmission and hinder recovery from burns, trauma, bleeding and surgery.
  • Japanese researchers have identified a hormone in the liver as a cause of insulin resistance, which could throw new light on how to treat diabetes.
  • Scientists from Saint Louis University have found that a crucial chemical in Turmeric used in Asian countries to treat liver damage from a condition known as fatty liver disease.
  • Researchers at the University of Colorado School of Medicine and The Children's Hospital have taken a big step toward understanding what causes one of the most serious liver diseases in infants.
  • A more personalized treatment for people with a type of metastatic liver cancer --hepatocellular carcinoma -- may be possible by targeting the protein c-Met, according to Penn State College of Medicine researchers. Hepatocellular carcinoma (HCC) is the number three cause of cancer deaths in the world.
  • Estimates of the prevalence of liver disease suggest that one‐third of the United States population has non‐alcoholic fatty liver disease (NAFLD).
  • Characteristics such as patient engagement, physician communication, and staff coordination may help to explain why some dialysis centers achieve higher patient survival rates than others, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).
  • Italian researchers report that liver transplant candidates who have a strong religious connection have better post-transplant survival. This study also finds that religiosity—regardless of cause of death—prolongs the life span of individuals who underwent liver transplantation. Full findings are now available online and in the October issue of Liver Transplantation. a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases (AASLD).
  • Researchers at Oregon Health & Science University have discovered that a form of cell division typically associated with cancer called multipolar mitosis can yield diverse, viable cells capable of protecting the liver from injury and poisonous substances, such as pesticides, carcinogens or drugs. Their findings are published online in the journal Nature.
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