Testosterone Replacement Therapy Effects: Increase Stroke And Heart Attack Risks For Men

Testosterone plays a significant role in a man’s development from muscle and bone mass to sexual functions. However, this hormone offers benefits when balanced but poor levels in the body could lead to health problems. 

Low testosterone levels affect many men across the world. In the U.S., 2 in every 100 men have the condition, according to the American Urological Association.

It commonly affects older men, with 50 percent of those over 80 years old are estimated to have poor levels of testosterone. But younger men can also experience the condition. 

Health conditions also contribute to testosterone levels. Having diabetes or being overweight have been linked to poor hormone count. 

Luckily, there are treatments available to increase testosterone. Testosterone replacement therapy (TRT) have been used by some men to regain energy levels, sex drive and mood. 

However, TRT has been known to have side effects, such as acne, disturbed breathing during sleep, breast swelling and high red blood cell counts. A new study adds more health problems to the list. 

Analyzed data from 15,401 men, aged 45 years or older, researchers found that TRT led to 21 percent higher risk of cardiovascular problems. Men were more likely to experience ischemic stroke, transient ischemic attack and myocardial infarction.

The risk appeared high in the first two years of therapy, the researchers said. The findings, published in the American Journal of Medicine, confirm previous claims that TRT could have major side effects. 

“Our findings show that the use of TRT was associated with an increased risk of stroke, TIAs or cardiac arrest during the first two years of use,” Christel Renoux, one of the researchers from McGill University in Canada, said in a statement. “We strongly recommend that clinicians proceed with caution when considering prescribing TRT and first discuss both the potential benefits and risks with patients.”

For the study, the researchers reviewed electronic medical records of patients from the United Kingdom. The team focused on men with low testosterone levels due to aging and not external factors. 

Renoux said there is limited evidence to support the long-term clinical benefits of TRT in men. However, Renoux also noted larger study is required to confirm their findings. 

Man Some people struggle to have a romantic relationship, get a sexual partner and experience parenthood due to environmental factors and health conditions. Pixabay