The Grapevine

Too Much Of These Vitamins Could Damage Hips

Taking vitamin supplements can help improve health and avoid diseases. However, people should take in moderation since having too much of certain vitamins in the body could be harmful. 

A new study, published in the journal JAMA Network Open, shows a link between the effects of vitamins B-6 and B-12 and the risk of hip fracture. Researchers analyzed data from 75,864 postmenopausal women. 

The team spent 20 years to observe the participants’ health, diet and intake of supplements. They also took into account the women’s recreational activities, medications, smoking habit and body mass index (BMI).

During the study, more than 2,300 hip fracture cases were recorded. All of these injuries did not occur due to major trauma, like vehicle accident, or cancer, Medical News Today reported Monday

The women who appeared with damaged hips reported high intake of B vitamin supplementation. Those who took both vitamins B-6 and B-12 had nearly 50 percent higher risk of fracture compared to women with a low intake of the supplements. 

The increase is higher when women took vitamins that "far exceeded the recommended dietary allowances," the researchers said. However, they noted they did not determine how vitamins B-6 and B-12 directly cause the fracture.

The team believed the side effects of ingesting high levels of B-6 contributed to the problems with the hips. Health experts said high doses of the vitamin could cause neurological symptoms, such as ataxia and decreased muscle tone. 

People experiencing these symptoms are then more likely to get injured from falling, which may damage their hips. The researchers also suggested that too much vitamin B-6 in the body could "accelerate bone loss by counteracting the modulating influence of estrogens on steroid receptors."

The study currently is the first of its kind to focus on the interaction between vitamin B-6, vitamin B-12 and hip fractures. The researchers said more research is needed to further understand the link between high vitamin intake and the risk of injury. 

“Although we acknowledge the limitations of our cohort design, the findings herein add to the body of literature that suggests caution should be used in vitamin supplementation when there is no apparent deficiency,” the researchers said. 

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