Depression isn’t a two-dimensional issue, and it’s not always the result of brain chemistry imbalances, trauma, genetics, or losing a loved one. There are, in fact, a variety of little known issues that can lead to depression — and many of them can sneak up on us without us even realizing it.

Being aware of these surprising factors can help you prevent them to begin with, or at least know how to tackle them when you come across them. Click on the slideshow to learn about several little known factors that can lead to depression.