Marijuana potency has nearly tripled in the past 20 years, and we know very little about the effect this could have on users, especially teenagers and adolescents whose brains have not fully developed. The Centers for Disease Control and Prevention recently revealed that, although cigarette use among American teens has dropped by 64 percent, marijuana use has doubled.

Evidence has shown that the effects of chronic marijuana use has on the brain depends heavily the person’s age when they first start using and how long they use for. So if marijuana is becoming more potent and people are starting to use it earlier, what does that say for their future? Here are five ways marijuana use can affect us later in life.