Liver could regulate the body weight, says a new study conducted at Molecular Obesity Laboratory, University of Melbourne.

The researchers found that liver plays a major role in controlling weight gain by communicating with the brain however this is only possible with saturated fat and wouldn’t necessarily stop weight gain caused by eating fatty foods.

An enzyme, FBPase, present in the liver is responsible for the production of glucose. The level of enzyme increases when it senses fatty food, which then sends a signal to the brain to suppress the expression of appetite stimulating genes.

People who eat a fatty diet would still become overweight, but the system probably limited the amount of weight gained, Dr Barbara Fam researcher at Melbourne University told AAP News.

The researchers at University of Melbourne conducted experiments in live mice models. They found that animals with more FBPase had only half the amount of fatty tissue and ate less food than those mice without the extra enzymes.

"We believe that this enzyme is really important in stopping the body from gaining any more weight, Dr Barbara Fam told AAP. Potentially, you could actually be a lot fatter if you don't have this enzyme being active," she added.