Depression is a common but serious mental illness that can affect how you feel, think, and act. Living with depression is often difficult and exhausting and leaves you feeling drained and down in the dumps. Luckily, there are supplements to help you out. Here are 14 of the best supplements for depression relief: (Note that these supplements don’t replace prescribed medication)

Happy Healthy Hippie Joy-Filled Supplement
photo: Happy Healthy Hippie

Happy Healthy Hippie’s Joy-Filled Supplement is currently 5% off. This completely plant-based anxiety and depression supplement provides total mood support with its blend of 7 healing herbs that have been used for centuries as natural mood enhancers. These herbs provide natural anxiety relief and act as a natural anti-depressant.

WellPath Zen Supplement
photo: WellPath

WellPath’s Zen Supplement is currently 5% off. This supplement is expertly curated to contain the optimal mix of adaptogens, herbs, and vitamins known to provide stress and depression relief. With natural mood enhancers like Passion Flower and Niacinamide along with energy-supporting Riboflavin and Magnesium, this supplement sharpens your mind and supports positive energy through the day.

LES Labs Mood Boost Supplement
photo: LES Labs

LES Labs’ Mood Boost Supplement is currently 5% off. This supplement’s natural formula helps to provide stress, anxiety, and depression relief quickly. It is formulated with 5-HTP, which naturally promotes a positive mood, L-Tyrosine and L-Theanine, which helps to relieve stress and anxiety, and GABA, which calms the mind and assists in mood support. It also contains a herbal blend that promotes relaxation and supports the body’s natural ability to cope with stress.

The Genius Brand Genius Joy
photo: The Genius Brand

The Genius Brand’s Genius Joy is formulated with SAM-e, Rhodiola, ginseng, and 11 more focus-boosting vitamins and minerals for mood support, and anxiety and depression relief. It also features a unique vitamin complex with B-12 and vitamin D, coupled with pure L-Theanine to reduce mental and physical stress while stabilizing your mood.

Dr. Emil Nutrition 5-HTP Plus Supplement
photo: Dr. Emil Nutrition

Dr. Emil Nutrition’s 5-HTP Plus Supplement contains 200mg of pure 5-HTP with clinically proven serotonin synthesizers, SAM-e, which is a well-known serotonin booster, and L-Tryptophan, which metabolizes into 5-HTP in the body. It also includes vitamin B6 which is vital in the conversion of 5-HTP into serotonin. This supplement increases serotonin levels, promoting a positive mood, anxiety and depression relief, and better sleep.

Arazo Nutrition 5-HTP Supplement
photo: Arazo Nutrition

Arazo Nutrition’s 5-HTP Supplement is currently 5% off with an additional $1 off on your first subscribe and save order. This supplement contains 200mg of 5-HTP, which is the primary precursor to serotonin production in the body. By increasing your serotonin levels, this supplement provides effective anxiety and depression relief, better sleep, and improved mood.

NutriRise Ashwagandha Supplement
photo: NutriRise

NutriRise’s Ashwagandha Supplement offers the most potent formula in the market with over 1300mg of organic ashwagandha root powder extract. Ashwagandha is an herb known to reduce cortisol, commonly known as the stress hormone, boost brain function, and fight symptoms of anxiety and depression. This supplement delivers superior anti-stress, anti-anxiety, and anti-depression support.

TWINLEAF Hemp Gummies
photo: TWINLEAF

TWINLEAF’s Hemp Gummies contains the safest and strongest professionally advanced formula with over 10,000mg. It is an ideal source of essential Omegas-3, 6, and 9 and vitamins that aid in enhancing your body and mind functions. Hemp has been shown to have antidepressant-like effects and provides anxiety relief as well in addition to lifting mood, relaxing the body and mind, and providing pain relief.

EvoNaturals Hemp Gummies
photo: EvoNaturals

EvoNaturals’ Hemp Gummies are currently $2 off. With nearly 300mg hemp each gummy, this supplement helps you deal with depression, stress, and anxiety. It is also a great source of vitamins E and B, and Omegas-3, 6, and 9. Hemp has been shown to relieve symptoms of anxiety and depression in addition to acting as a natural painkiller, lifting mood, and reducing stress.

Physician’s Choice Ashwagandha Supplement
photo: Physician’s Choice

Physician’s Choice’s Ashwagandha Supplement is currently 5% off. This Ashwagandha supplement is a natural anti-anxiety and anti-depression supplement made from Ayurveda herbs. It provides maximum cortisol relief, adrenal support, and even helps your thyroid levels maintain homeostasis.

NusaPure St. John’s Wort Supplement
photo: NusaPure

NusaPure’s St. John’s Wort Supplement is made with St. John’s Wort which contains a natural active chemical called Hypericin which helps balance brain chemistry, resulting in improved mood. This herbal mental aid also helps relieve symptoms of depression and anxiety in addition to enhancing brain function.

Zhou Nutrition Calm Now Supplement
photo: Zhou Nutrition

Zhou Nutrition’s Calm Now Supplement is currently 5% off. This supplement was formulated with the modern busy person in mind. It supports serotonin production while at the same time easing you into a calm and centered headspace. This supplement combines the best of Eastern herbal tradition and modern research to deliver a supplement that relieves symptoms of depression and anxiety and lifts your mood.

NatureWise 5-HTP Plus Supplement
photo: NatureWise

NatureWise’s 5-HTP Plus Supplement is currently $2 off. This supplement delivers a potent 200mg dose of 5-HTP enhanced with vitamin B6 for better absorption and effectiveness. It naturally converts into serotonin in the brain to support a balanced mood and healthy sleep patterns as well as provide anxiety and depression relief.

WELLBIES Hemp Gummies
photo: WELLBIES

WELLBIES’ Hemp Gummies are currently $2 off. These gummies are formulated with 30,000mg of hemp and help you adjust to problematic situations by keeping your mind sharp and you in high spirits. This supplement reduces anxiety, supports mood stabilization, decreases hormonal imbalances, removes stress, lifts your mood, and acts as a natural anti-depressant.